Itemized deductions include things like mortgage interest, property taxes and charitable donations. You get to choose whether to itemize or use the standard deduction. If your standard deduction is more than the total of your itemized deductions, you will use that to get the best refund.
Medical expenses and Miscellaneous expenses (for example tax preparation fee or unreimbursed job expenses) are also part of your itemized deductions. However, these two categories are not fully deductible; the amount that’s deductible has to be over 10% for medical, and 2% for miscellaneous.